ABSTRACT
<p><b>AIM</b>To study the chemical consitituents of the n-butanol-extracts of Anabasis salsa and Various chromatographic techniques were used to the chloroform-extract of Anabasis brevifolia.</p><p><b>METHODS</b>separate and purify the constituents. Their physico-chemical properties and spectral data were used to elucidate their structures.</p><p><b>RESULTS</b>Five compounds were isolated and identified as 2-O-beta-D-glucopyranosyloxy-4,6-dimethoxy phenylenthanone (1), 2-O-(2)-beta-D-glucopyranosyloxy-4, 6-dimethoxy phenylenthanone (2), 3-methyl-but-2-enoic acid-[2-(4-methoxy phenyl)-ethyl]-amide (3), 5,6,7,2'-tetramethoxy isoflavonoid (4), 2'-hydroxy-5,6,7-trimethoxyisoflavonoid (5).</p><p><b>CONCLUSION</b>Compounds 2, 3, and 5 are new compounds. And the others were isolated from Anabasis L. for the first time.</p>
Subject(s)
Chenopodiaceae , Chemistry , Crotonates , Chemistry , Glucosides , Chemistry , Isoflavones , Chemistry , Molecular Structure , Plants, Medicinal , ChemistryABSTRACT
<p><b>AIM</b>To study the impurity in the drug megestrol acetate.</p><p><b>METHODS</b>Chromatography methods were used to separate the chemical constituents. Their structures were determined by NMR and MS spectral analysis.</p><p><b>RESULTS</b>Two new epimers were isolated from the mother liquid of the drug megestrol acetate.</p><p><b>CONCLUSION</b>These new epimers were identified as 17alpha-acetoxy-2beta,6alpha-dimethylprega-4-ene-3,20-dione (1) and 17alpha-acetoxy-2alpha,6alpha-dimethylprega-4-ene-3,20-dione (2).</p>
Subject(s)
Drug Contamination , Megestrol Acetate , Chemistry , Molecular Conformation , Molecular Structure , Pregnanediones , Chemistry , StereoisomerismABSTRACT
<p><b>AIM</b>To study the impurity of the drug testosterone.</p><p><b>METHODS</b>Chromatography methods were used to separate the chemical constituents. Their structures were determined by NMR and MS spectral analysis.</p><p><b>RESULTS</b>Two new epimers were isolated from the mother liquid of the drug.</p><p><b>CONCLUSION</b>These new epimers were identified as 3alpha-ethoxyandrost-4-en-17beta-ol, 3beta-ethoxyandrost-4-en-17beta-ol.</p>